YCombinator Spring 2026 Startup Database

Alchemy

Natural-language image analysis for life-sciences labs.

Keyframe Labs

Turn agents into lifelike real-time video calls.

Adialante

Compact mobile MRI for cancer screening without fixed scanner infrastructure.

Lumius

Real-time 3D ultrasound for vascular access and procedure guidance.

Prototyping.io

CAD-to-part automation for mechanical parts.

Mount

Mount secures, risk-scores, and insures deployed AI agents.

Sidekick

SMS-native AI assistant answers frontline worker questions from company documents.

AICE Power

Clip-on sensors find commercial building energy waste in real time.

Complir

Automates physical product compliance for cross-border retailers.

Harbor

Turns trial protocols and source documents into AI-built EDC workflows.

Alchemize

AI-native customs brokerage for faster importer compliance.

Smol machines

Packages software as fast, portable virtual machines.

Archer

Turns plain-English reward rules into automated payouts.

Minicor

Self-healing desktop automation for legacy systems.

Datost

Slack-native AI analyst that answers business questions from connected systems.

Zibra Labs

Ray-grade cluster execution for quant backtesting at scale.

Ara

Voice-first Mac agent that operates the computer by speech.

PLAN0 AI

Turns architectural plans into construction cost intelligence.

Armature

Tests agent workflows across MCP and CLI surfaces.

Aseon Labs

Builds robotic pitstops that reset autonomous vehicle fleets.