Zeitgeist Startup Directory - What the world's best startups are building

Startup Intelligence Database

Discover what the world's best startups are building before it's announced publicly.

Showing companies

No Clear ML Differentiation

FinalDose

Programmable DNA drug platform for genetically defined cancer targets.

A reusable DNA-sensing kill-switch molecule would turn genetic cancer drivers into programmable drug targets if delivery and specificity work.

Healthcare

Bio Therapeutics

YC Spring 26

May 18, 2026

Model Evaluation

RAG

Workflow Agent

Data Extraction

Speech AI

TakeCareOS

Atlas turns care-agency back office records into approved operational actions.

Atlas gives a one-person YC company a sharp wedge into regulated care operations where admin labor, billing errors, and audit risk are constant.

Healthcare

Care Operations

YC Spring 26

May 18, 2026

Model Evaluation

RAG

Workflow Agent

Data Extraction

Optimization

Clara

AI primary care that reads records and drafts physician-reviewed care.

Clara pairs Circle Medical operating experience with an AI-first care model where the scarce asset is full-chart context plus clinician review efficiency.

Healthcare

Primary Care

YC Spring 26

May 18, 2026

Model Evaluation

RAG

Workflow Agent

Personalization

Fuchsia

AI gets hardware compliance done in weeks, not months.

Fuchsia turns hardware certification into a software-like workflow at the moment lab rules and supply chains are getting harder to manage.

Industrial

Hardware Compliance

YC Spring 26

May 18, 2026

Speech AI

Imperfect

Adaptive AI coaching for endurance athletes with messy lives.

Imperfect’s wedge is adaptive coaching for serious amateurs, with founder fit from Garmin data tooling and consumer fintech product building.

Healthcare

Athletic Coaching

YC Spring 26

May 18, 2026

Model Evaluation

RAG

Workflow Agent

Speech AI

Optimization

Cignara

Enterprise AI voice and chat agents for B2C support and sales.

Cignara turns enterprise contact centers into revenue surfaces by pairing governed voice agents with buyer-specific knowledge graphs and founder-led enterprise AI experience.

Technology

Voice Agents

YC Spring 26

May 18, 2026

Computer Vision

9 Mothers

AI point-defense turret for close-range drone threats.

Passive acoustic cueing plus visual tracking gives 9 Mothers a narrow, high-urgency wedge in close-range counter-drone defense.

Industrial

Drone Defense

YC Spring 26

May 18, 2026

Model Evaluation

Workflow Agent

Data Extraction

Prediction

Netter

Turn messy operational data into AI-built workflows, apps, and ML pipelines.

Netter compresses data engineering and applied ML implementation into a chat-led operations platform for companies that lack large internal data teams.

Technology

Data Ops

YC Spring 26

May 18, 2026

Model Evaluation

RAG

Workflow Agent

Anomaly Detection

Sazabi

Agent-native observability that turns logs into incident answers.

The bet is that coding-agent adoption makes dashboard-first observability too slow, giving Sazabi a timing edge around logs-first, agent-native incident response.

Technology

Dev Tools

YC Spring 26

May 18, 2026

Model Evaluation

Workflow Agent

Optimization

Superset

Orchestrates parallel coding agents across isolated workspaces.

Superset turns coding-agent adoption into an orchestration layer, with timing, open-source distribution, and review workflow as the wedge.

Technology

Dev Tools

YC Spring 26

May 18, 2026

No Clear ML Differentiation

Inth

Developer-native consent infrastructure for web teams.

Inth turns consent from a legal dashboard into developer infrastructure, using open source adoption as distribution into a slow CMP category.

Technology

Privacy Infrastructure

YC Spring 26

May 18, 2026

Model Evaluation

RAG

Workflow Agent

Data Extraction

Fraud and Risk Scoring

Regbase

Finds and tracks obscure regulatory changes across jurisdictions.

Regbase's edge is source discovery: it targets obscure public-sector records that generic legal AI and search miss.

Technology

Regulatory Intelligence

YC Spring 26

May 18, 2026

Bloom

Brand OS for agentic marketing creative.

If agents become marketing operators, Bloom can own the persistent brand context they call before creating customer-facing work.

Marketing

Brand AI

YC Spring 26

May 18, 2026

No Clear ML Differentiation

Dispatch

Builds return satellites for in-space manufacturing payloads.

The bet is that downmass, not launch, becomes the scarce utility for in-space manufacturing, and Dispatch can own that return layer early.

Industrial

Space Manufacturing

YC Spring 26

May 18, 2026

Model Evaluation

RAG

Workflow Agent

Data Extraction

Optimization

Hedge

Automates wholesale specialty insurance placement for retail brokers

Hedge turns the manual E&S wholesale layer into software-mediated placement, with founders who have built AI brokerage and AI ops systems.

Finance

Specialty Insurance

YC Spring 26

May 18, 2026

No Companies Found

What The World's Best Startups Are Building

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Rating

Startup Intelligence Database

FinalDose

Programmable DNA drug platform for genetically defined cancer targets.

TakeCareOS

Atlas turns care-agency back office records into approved operational actions.

Clara

AI primary care that reads records and drafts physician-reviewed care.

Fuchsia

AI gets hardware compliance done in weeks, not months.

Imperfect

Adaptive AI coaching for endurance athletes with messy lives.

Cignara

Enterprise AI voice and chat agents for B2C support and sales.

9 Mothers

AI point-defense turret for close-range drone threats.

Netter

Turn messy operational data into AI-built workflows, apps, and ML pipelines.

Sazabi

Agent-native observability that turns logs into incident answers.

Superset

Orchestrates parallel coding agents across isolated workspaces.

Inth

Developer-native consent infrastructure for web teams.

Regbase

Finds and tracks obscure regulatory changes across jurisdictions.

Bloom

Brand OS for agentic marketing creative.

Dispatch

Builds return satellites for in-space manufacturing payloads.

Hedge

Automates wholesale specialty insurance placement for retail brokers