Recursion Pharmaceuticals, Insilico Medicine, Owkin, BenevolentAI, Bioptimus
Tempus AI, Cradle Bio, Enveda Biosciences
Scale AI, Encord
Foundation models that predict missing biological data modalities from routine samples. State-of-the-art spatial proteomics prediction validated by benchmark results. Petabyte-scale spatial biology platform experience is rare. If pharma companies adopt Strand's predictions as standard, switching means losing modality prediction capabilities that influence trial design.
Using multimodal foundation model imputation across omics, LLM-RAG metadata normalization, and multimodal biomarker discovery.
Simulates human biology with AI to predict drug effects and run virtual trials.
Google CEO Sundar Pichai highlighted their C2S-Scale 27B model for generating a novel cancer hypothesis that was later validated experimentally. CellType simulates human biology to predict drug effects using foundation models presented at ICML 2024, with all deals coming inbound from top-10 pharma. Yale professor turned down Google to build it.
Mines parasite genomes to discover protein therapeutics for autoimmune diseases.
Parasites evolved to suppress human immune responses over millions of years. Ditto mines their genomes for immunomodulatory proteins, and over 98% of those proteins remain uncharacterized. Three PhDs from Harvard, Berkeley, and UCSF with 40+ years of combined expertise in host-parasite biology.
Automates surgical planning for orthopedic procedures from CT scans using agentic AI.
Surgical planning for shoulder replacements takes hours of manual CT scan interpretation. Mango automates it in seconds via API, already past $500K ARR before demo day, with an 8-figure LOI from a leading orthopedic company. Only company in YC W26 pursuing FDA 510(k) clearance.